Research

Neuroplasticity and Its Dark Sides
April 25, 2019
PAIN Its Anatomy, Physiology and Treatment, Third Edition
May 7, 2019

Research

My research has concerned, first the function of the middle ear and the cochlea, then the neuroscience of the auditory system, somatosensory and visual systems and of hyperactive motor disorders. I have used systems identification methods such as Winer kernel analysis of recordings from single nerve cells in the cochlear nucleus using pseudorandom noise stimuli. I have developed computer algorithms for automatic identification of human chromosomes, I discovered the role of protuberances on the eyes of certain insects and I have studied the electrical potentials of the eye.  More recently I have studied neuroplasticity and its role in disorders such as tinnitus, hyperacusis and hyperactive motor disorders. I am particularly interested in the role of neuroplasticity in disorders such as severe tinnitus, chronic neuropathic pain and spasticity and muscle spasm. I am involved in tinnitus research through my involvement with the international research organization "Tinnitus Research Initiative" (TRI). I organized the TRI Annual Conference in 2010 here in Dallas, and I am Chairman of the TRI Foundation I have also studied the role of the non-classical auditory pathways and their involvement in disorders such as tinnitus.

Intraoperative neurophysiological monitoring

I developed methods for intraoperative neurophysiological monitoring, especially for preserving the function of cranial nerves. The use of these methods has reduced the risk of serious complications such as loss of the function of mimic muscles from damage to the facial nerve in surgical operations to remove vestibular Schwannoma. These methods have also reduced the risks of serious complications in many other operations in the brain such as operations for large skull base tumors.

Books

I am the author of 19 (single author) professional books on the anatomy and physiology of sensory systems, hearing science, neuroscience of pain, intraoperative neurophysiologic monitoring and neuroplasticity. My most recent book is "Neuroplasticity and its Dark Sides: Disorders of the Nervous System". The third edition of my book “Pain: Its Anatomy, Physiology and Treatment” and the second edition of “Plasticity and its Dark Sides were published 2018. I have been editor or co-editor of seven published books, most recently, "Textbook of Tinnitus", 95 chapters and 785 pages, published by Springer 2010. I am the author of 98 chapters in professional in professional books. I am the author or co-author of more than 200 articles in refereed journals. One of my books have been translated to Japanese and two have been translated to Chinese.

Editorship in Scientific journals

I was the Editor-in-Chief (and founder) of the international journal, Hearing Research for 27 years (1978-2005); I am member of the Editorial Board of many other international journals.

Teaching

I have developed new courses in the Neuroscience Program of the School of Behavioral and Brain Sciences The University of Texas at Dallas.

1. "Biology of Pain", 2. "Sensory Systems", 3. "Neural

2. Plastic and Disorders of the Nervous System", 4. "Functional Human Neuroanatomy" and 5.
“Intraoperative Neurophysiological Monitoring”.

Recent publications in refereed journals (of a total of 210)

1. Engineer ND, Møller AR, Kilgard MP. Directing neural plasticity to understand and treat tinnitus. Hear Res. 2013 Jan; 295(1-2):58-66.
2. Møller AR The Role of Neuroplasticity and the Immune System in Recovery from Strokes and Other Forms of Brain Trauma. J. Neurol & Stroke. 2014 1(3) 1-2.
3. Møller, A.R, Salvi, R., De Ridder D., Kleinjung T., Vanneste S. Eds. “Pathology of tinnitus and hyperacusis-clinical implications, Editorial” BioMed Research International within the Otolaryngology Subject, 2015 BioMed Research International, Volume 2015, Article ID 608437,
4. Vedantam S. and Møller A.R. (2015) Minocycline: A Novel Stroke Therapy. J Neurol Stroke 2(6): 00073. DOI: 10.15406/jnsk.2015.02.000.
5. Møller AR (2015) New Developments in Neuroscience, Journal of Integrated Studies, 2015, pp 1-23, 2015
6. Møller, A.R. (2016) Sensorineural Tinnitus- Its Pathology and Probable Therapies, Review. International Journal of Otolaryngology, vol 2016, Article ID 2830157, 13 pages
7. Møller, A.R. (2019) New Developments in Neuroscience. A Review, Archives of Neurology and Neurosurgery, 2, 48-58.

Recently published books (of a total of 19)

1. Møller, A.R. Hearing: Anatomy, physiology, and disorders of the auditory system, 3 rd Edition, 415 pages. San Diego Plural Publishing, Inc. 2012 ISBN-13: 978-1-59756-427-4, ISBN-10: 1-59756-427-3.
2. Møller, A.R. Sensory Systems, 2nd Edition. Aage R. Møller Publishing, Dallas 2014. 417 pages, ISBN-13: 978-1478175872, ISBN-10: 1478175877.
3. Møller, A.R. (2018) Pain: Its Anatomy, Physiology and Treatment, 3 rd Edition. Aage R. Møller Publishing, Dallas, 2018, 361 pages, ISBN 9781729634844.
4. Møller, A.R. Neuroplasticity and its Dark Sides: Disorders of the Nervous System, 2 nd Ed. Aage R. Møller Publishing, Dallas, 2018, 244 pages, 2018. ISBN-13: 978-1981464906 ISBN- 10: 1981464905

Recent book chapters authored (of a total of 111)

1. Møller, A.R. Intraoperative Neurophysiological Monitoring Techniques in Cavernous Sinus Surgery. Chapter 23, In: Loftus, CM, Biller, J. and Baron, EM Eds. Intraoperative Neuromonitoring. McGraw Hill Education pp255-260, 2014

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2. Møller, A.R. Intraoperative Neurophysical Monitoring Techniques for Microvascular Decompression Procedures. In: Loftus, CM, Biller, J. and Baron, EM Eds. Intraoperative Neuromonitoring. McGraw Hill Education, pp273-284, 2014.
3. Møller, A. R. “Sensory Transduction” in The SAGE Encyclopedia of Theory in Psychology. Harold L. Miller Jr. Editor, DOI: http://dx.doi.org/10.4135/9781483346274.n287 January 2016
4. Møller, A. R. Pathogenesis and Treatment of Hemifacial Spasm, in: Microvascular Decompression Surgery, Li, Shi-Ting, Zhong, Jun, Sekula, Jr., Raymond F. (Eds.) pp 35-49, Springer, 2016.
5. Møller, A. R. Microvascular Decompression Surgery for Disabling Positional Vertigo and Tinnitus, in: Microvascular Decompression Surgery, Li, Shi-Ting, Zhong, Jun, Sekula, Jr., Raymond F. (Eds.) pp 95-101, Springer, 2016.

Books co-edited recently (of a total of 9)

1. Møller A.R. (ed.) Cochlear implants and auditory brainstem implants. Karger 228 pages; 2006.
2. Møller A.R. (ed.) Reprogramming the Brain, Progress in Brain Research vol 157, Elsevier Science. 2006.
3. Langguth, B., G. Hajak, T. Kleinjung, A. Cacace & A.R. Møller (Eds.) Tinnitus: Pathophysiology and Treatment, Progress in Brain Research, Vol. 166, Elsevier, Amsterdam, 2007 Langguth, B., G. Hajak, T. Kleinjung, A. Cacace & A.R. Møller (Eds.) Progress in Brain Research, Vol. 166, Elsevier, Amsterdam, 542 pages, 2007.
4. Møller, A.R., B. Langguth, D. De Ridder and T. Kleinjung. Textbook of Tinnitus, Springer, New York, 785 pages, 2011. (Translated into the Chinese language and published by Shanghai Scientific & Technical Publishers in China, July, 2015, Chinese ISBN: 978-7-5478-2519-8).

Honors, Awards and other Recognitions

1. Fellow of the Acoustical Society of America (1970)
2. Fellow of the American Society of Neurophysiological Monitoring
3. Senior Fellow of the American Neurotology Society (1990)
4. Honorary Member, Italian Society of Audiology, Italy (1990).
5. Corresponding (Honorary) Member, Die Physikalisch-Medicinische Societat, Germany (1989).
6. Elleman Lecture: Vascular compression of the facial nerve in hemifacial spasm: Neurophysiological concepts.” Departments of Neurology and Neurosurgery, Neurochirurgische Klinik, Berne University Hospital, Berne, Switzerland, 1991.
7. Hallowell Davis Lecture: “Auditory evoked potentials in intraoperative monitoring.” International Electric Response Audiometry Study Group XII Biennial Symposium, Terme Di Comano, Italy, September 27, 1991.
8. The American Society of Intraoperative Monitoring (ASNM) “Award of Excellence” (2001)
9. Presidential lecture, Annual Meeting of the American Society of Neurophysiologic
10. “Honorary Diplomat” American Board of Neurophysiologic Monitoring” (2003)
11. Honored by a Special Issue of the journal Hearing Research (vol 216-217, 2006)
12. “Teacher of the Year “, School of Behavioral and Brains Sciences, (2007)

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13. "The President's Teaching Excellence Award" The University of Texas at Dallas for the
Academic Year 2010-2011.
14. House of Representative Recognition, Pete Sessions, June 2, 2011
15. Gifford K. Johnson Community Leadership Award, 2012
16. Named Distinguished Lecturer in Cognition and Neuroscience, at the School of Behavioral and Brain Sciences, 2012
17. Polycarp Kush Lecture at The University of Texas at Dallas, 2012
18. “Leo Happel Lecture” at LSU School of Medicine Department of Neurosurgery May 25, 2012. “Neural Plasticity for Good and Bad”
19. Named Founders Professor of Neuroscience, 2013
20. Honorable Editor for Journal of Neurology & Stroke, 2014

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